Studies Find DNA Damage Long Term In Smokers

Studies Find DNA Damage Long Term In Smokers
Many people who continue to smoke despite knowing all the negative impacts. Ranging from cancer, heart attacks, impotence to pregnancy and fetal disorders have been understood as the evil effects of smoking. Now, an American study found a new reason which is expected to prevent the smokers to continue smoking.

Research conducted by Harvard Medical School and the Hebrew SeniorLife Institute for Aging Research found results that smoking can cause damage to DNA (deoxyribose Nucleic Acid) which will take place until more than 30 years after the smoker quit.

The study used blood samples from 16ribu people, including active smokers, former smokers, to those who never smoked at all.

The researchers then report their findings have evidence of tobacco pengasup 'signs' that is not lost in the long term, which then contributes to lung disease and heart.

"Our study has found evidence that smoking has long-term effects on the molecular machinery of the body," said Roby Joehanese research instructor in a report published in the American Heart Association journal, Circulation: Cardiovascular Genetics.

In the note explained also that the focus of this study is to find the effect of smoking on DNA methylation, which regulates gene expression.

According to the researchers, these methylation genes occurred in a person negatively affected by smoking, such as cancer, osteoporosis, heart and cardiovascular disorders.

Approximately one in three smokers later discovered genes undergo methylation. While most of these genes back to a normal level of five years after the person stops, changes in 19 genes-including TIAM2 gene, which is associated with limfoma- still take up to 30 years.

"The good thing is that when one moment you stop smoking, the majority mark DNA methylation is going to be gradually returning to normal levels after five years. This means that your body was trying to heal the effects of the evil of smoking tobacco," said Joehanese, quoted from Huffington Post.

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